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Rabbit Anti-TZFP/ZNF538/AP Conjugated antibody (bs-8007R-AP)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-8007R-AP
英文名稱1 Rabbit Anti-TZFP/ZNF538/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的范可尼綜合征相關(guān)鋅指蛋白抗體
別    名 FANCC interacting protein; FANCC-interacting protein; Fanconi anemia zinc finger protein; FAXF; FAZF; OTTHUMP00000045790; repressor of GATA; Rog; Testis zinc finger protein; ZBT32_HUMAN; Zbtb32; ZBTB32 protein; Zinc finger and BTB domain containing 32; Zinc finger and BTB domain-containing protein 32; Zinc finger protein 538; ZNF538.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 轉(zhuǎn)錄調(diào)節(jié)因子  鋅指蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, Cat, )
產(chǎn)品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 53kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TZFP/ZNF538
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 Function:
DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor. Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T cells.

Subunit:
Homodimer (via PTB domain). Interacts with the N-terminal of FANCC. Interacts with ZBTB16. Interacts with GATA3 (By similarity).

Subcellular Location:
Nucleus. Located in nuclear speckles.

Tissue Specificity:
Predominantly expressed in testis. Some isoforms are ubiquitously expressed.

Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 1 BTB (POZ) domain.
Contains 3 C2H2-type zinc fingers.

Database links:

Entrez Gene: 27033 Human

Entrez Gene: 58206 Mouse

Entrez Gene: 688845 Rat

Omim: 605859 Human

SwissProt: Q9Y2Y4 Human

SwissProt: Q9JKD9 Mouse

Unigene: 99430 Human

Unigene: 116789 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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