產(chǎn)品編號(hào) | bs-12377R-Gold |
英文名稱1 | Rabbit Anti-OSR1 + OSR2/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的OSR1/OSR2蛋白抗體 |
別 名 | FLJ90037; Odd skipped related 2; Odd skipped related 2A protein; Odd-skipped related; odd-skipped related 2 (Drosophila); Osr2; OSR2_HUMAN; Protein odd-skipped-related 2; ODD; Odd skipped Drosophila homolog; Odd skipped homolog; Odd skipped related 1 (Drosophila); Odd skipped related 1; Odd skipped related 1 Drosophila; Odd1; Protein odd skipped related 1; OSR1_HUMAN. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 細(xì)胞生物 發(fā)育生物學(xué) 干細(xì)胞 鋅指蛋白 表觀遺傳學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse, Rat, (predicted: Human, Dog, Pig, Cow, Horse, Sheep, Danio rerio) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 35kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human OSR2 and OSR1 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: OSR2 is a 312 amino acid protein that contains five zinc finger domains. It is expressed in the kidneys, skeletal muscle, testis, and mouse embryos and may be involved in transcriptional activity and osteoblast function. The expression of OSR2 is regulated by C/EBP regulatory elements. OSR2 plays a role in regulating palatal development and expression of alkaline phosphatase. Two isoforms, OSR2A and OSR2B, are produced due to alternative splicing. OSR2B is 36 amino acids shorter than OSR2A and contains only three zinc finger motifs. Both isoforms localize to the nucleus and are thought to exhibit opposite transcriptional activities. Mutations in the gene encoding OSR2 can alter the gene expression of Pax-9 and TGF beta3. Subcellular Location: Nucleus. Similarity: Belongs to the Odd C2H2-type zinc-finger protein family. Contains 5 C2H2-type zinc fingers. Database links: Entrez Gene: 130497 Human Entrez Gene: 23967 Mouse Omim: 608891 Human SwissProt: Q8TAX0 Human SwissProt: Q9WVG7 Mouse Entrez Gene: 116039 Human Entrez Gene: 107587 Mouse Omim: 611297 Human SwissProt: Q8N2R0 Human SwissProt: Q91ZD1 Mouse Unigene: 253247 Human Unigene: 46336 Mouse Unigene: 13228 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |