產(chǎn)品編號(hào) | bs-13885R-BF488 |
英文名稱1 | Rabbit Anti-CHADL/BF488 Conjugated antibody |
中文名稱 | BF488標(biāo)記的軟骨蛋白樣蛋白抗體 |
別 名 | AY100452; CHADL; CHADL_HUMAN; Chondroadherin-like protein; D930017K21Rik; mCG_8786; RP4-756G23.1; SLRR4B. |
規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
說 明 書 | 100ul |
研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞骨架 細(xì)胞外基質(zhì) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Pig, Horse, Rabbit, ) |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 79kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human CHADL |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: Members of the small leucine-rich proteoglycan (SLRP) family are mostly extracellular proteins that function upstream of multiple signaling cascades. They affect intracellular phosphorylation and modulate distinct pathways, such as those driven by Toll-like receptors, TGF∫ and receptor tyrosine kinases. As a member of the SLRP family, CHADL (Chondroadherin-like protein) is a 762 amino acid protein containing 21 LRR (leucine-rich) repeats, which promote protein-ligand interactions. Chondroadherin, a closely related protein, promotes attachment of chrondocytes, osteoblasts and fibroblasts and also plays an important role in the regulation of chrodrocyte proliferation and growth. CHADL is a secreted protein that is located in the extracellular space. There are two isoforms of CHADL that exist as a result of alternative splicing events. Subcellular Location: Secreted; extracellular space; extracellular matrix. Similarity: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class IV subfamily. Contains 19 LRR (leucine-rich) repeats. Contains 2 LRRCT domains. Contains 2 LRRNT domains. Database links: Entrez Gene: 150356 Human SwissProt: Q6NUI6 Human Unigene: 344488 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |