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Rabbit Anti-Catalase/AP Conjugated antibody (bs-6874R-AP)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-6874R-AP
英文名稱(chēng)1 Rabbit Anti-Catalase/AP Conjugated antibody
中文名稱(chēng) 堿性磷酸酶(AP)標(biāo)記的過(guò)氧化氫酶抗體
別    名 Cas1; CAT; Cs1; MGC138422; MGC138424; CATA_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  發(fā)育生物學(xué)  神經(jīng)生物學(xué)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Mouse, Rat,  (predicted: Human, Horse, )
產(chǎn)品應(yīng)用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 60kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Catalase
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Catalase is the classical marker for peroxisomes and is the most abundant protein within peroxisomes. It is found in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.

Function:
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.

Subunit:
Homotetramer.

Subcellular Location:
Peroxisome.

Post-translational modifications:
The N-terminus is blocked.

DISEASE:
Defects in CAT are the cause of acatalasemia (ACATLAS) [MIM:614097]. A metabolic disorder characterized by absence of catalase activity in red cells and is often associated with ulcerating oral lesions.

Similarity:
Belongs to the catalase family.

Database links:

Entrez Gene: 847 Human

Entrez Gene: 12359 Mouse

Entrez Gene: 24248 Rat

Omim: 115500 Human

SwissProt: P04040 Human

SwissProt: P24270 Mouse

SwissProt: P04762 Rat

Unigene: 502302 Human

Unigene: 4215 Mouse

Unigene: 3001 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

過(guò)氧化氫酶是催化過(guò)氧化氫分解成氧和水的酶,存在于細(xì)胞的過(guò)氧化物體內(nèi)。過(guò)氧化氫酶是過(guò)氧化物酶體的標(biāo)志酶, 約占過(guò)氧化物酶體酶總量的40%。過(guò)氧化氫酶存在于所有已知的動(dòng)物的各個(gè)組織中,特別在肝臟中以高濃度存在。過(guò)氧化氫酶在食品工業(yè)中被用于除去用于制造奶酪的牛奶中的過(guò)氧化氫。過(guò)氧化氫酶也被用于食品包裝,防止食物被氧化。
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