| 產(chǎn)品編號(hào) |
bs-6554R-BF647 |
| 英文名稱1 |
Rabbit Anti-NOL8/BF647 Conjugated antibody
|
| 中文名稱 |
BF647標(biāo)記的核仁蛋白8抗體 |
| 別 名 |
C9orf34; NOL8; NOL8_HUMAN; NOP132; Nucleolar protein 8; Nucleolar protein Nop132. |
| 規(guī)格價(jià)格 |
100ul/2980元
購(gòu)買 大包裝/詢價(jià) |
| 說(shuō) 明 書 |
100ul
|
| 研究領(lǐng)域 |
腫瘤 腫瘤細(xì)胞生物標(biāo)志物 表觀遺傳學(xué) |
| 抗體來(lái)源 |
Rabbit |
| 克隆類型 |
Polyclonal |
| 交叉反應(yīng) |
(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
|
| 產(chǎn)品應(yīng)用 |
IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 |
132kDa |
| 性 狀 |
Lyophilized or Liquid |
| 濃 度 |
1mg/ml |
| 免 疫 原 |
KLH conjugated synthetic peptide derived from human NOL8 (841-885aa) |
| 亞 型 |
IgG |
| 純化方法 |
affinity purified by Protein A |
| 儲(chǔ) 存 液 |
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 |
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background:
Summary: NOL8 binds Ras-related GTP-binding proteins (see MIM 608267) and plays a role in cell growth
Function:
Plays an essential role in the survival of diffuse-type gastric cancer cells. May be involved in regulation of gene expression at the post-transcriptional level or in ribosome biogenesis in cancer cells.
Subunit:
Interacts with the GTP form of RRAGA, RRAGC and RRAGD. Interacts with NIP7. Interacts with DDX18; the interaction is RNA-dependent. Interacts with DDX47; the interaction is RNA-dependent.
Subcellular Location:
Nucleus, nucleolus. Note=Localizes in the nucleolar-organizing region during ribosome biogenesis.
Tissue Specificity:
Expressed in various diffuse-type gastric cancers. Detected at lower levels in skeletal muscle.
Post-translational modifications:
Phosphorylated
Similarity:
Contains 1 RRM (RNA recognition motif) domain.
Database links:
UniProtKB/Swiss-Prot: Q76FK4.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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