產(chǎn)品編號 | bs-20309R |
英文名稱 | Rabbit Anti-DHX38 antibody |
中文名稱 | DHX38蛋白抗體 |
別 名 | ATP dependent RNA helicase DHX38; ATP-dependent RNA helicase DHX38; DDX38; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 38; DEAH (Asp-Glu-Ala-His) box polypeptide 38; DEAH box protein 38; DHX38; KIAA0224; Pre mRNA splicing factor ATP dependent RNA helicase PRP16; Pre-mRNA splicing factor 16; Pre-mRNA-splicing factor ATP-dependent RNA helicase prp16; Prp16; PRP16 homolog of S.cerevisiae; pre-mRNA splicing factor ATP-dependent RNA helicase PRP16; PRP16_HUMAN; PRPF16. |
Specific References (1) | bs-20309R has been referenced in 1 publications.
[IF=5.722] Zou, Xiaopan. et al. ZMIZ2 promotes the development of triple-receptor negative breast cancer. Cancer Cell Int. 2022 Dec;22(1):1-16 WB ; Human.
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研究領(lǐng)域 | 細胞生物 發(fā)育生物學(xué) 細胞分化 表觀遺傳學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Cow) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 140kDa |
細胞定位 | 細胞核 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human DHX38: 201-300/1277 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a member of the DEAD/H box family of splicing factors. This protein resembles yeast Prp16 more closely than other DEAD/H family members. It is an ATPase and essential for the catalytic step II in pre-mRNA splicing process. [provided by RefSeq, Jul 2008] Function: Probable ATP-binding RNA helicase involved in pre-mRNA splicing. Subcellular Location: Nucleus. Similarity: Belongs to the DEAD box helicase family. DEAH subfamily. PRP16 sub-subfamily. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain. SWISS: Q92620 Gene ID: 9785 Database links: Entrez Gene: 9785 Human Entrez Gene: 64340 Mouse GenBank: NM_014003 Human Omim: 605584 Human SwissProt: Q92620 Human Unigene: 151218 Human Unigene: 23705 Mouse Unigene: 108087 Rat |