| 產(chǎn)品編號 | bs-6755R |
| 英文名稱 | Rabbit Anti-ZNF146 antibody |
| 中文名稱 | 鋅指蛋白146抗體 |
| 別 名 | Only zinc finger protein; OZF; OZF_HUMAN; Zfp146; Zinc finger protein 146; Zinc finger protein OZF; ZNF146; MGC125660; MGC125661. |
| 研究領(lǐng)域 | 腫瘤 腫瘤細(xì)胞生物標(biāo)志物 鋅指蛋白 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 33kDa |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ZNF146: 121-220/292 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Tissue specificity: Liver, skeletal and heart muscle, mammary cells. Very low levels in brain, lung, placenta and kidney. Strongly overexpressed in many pancreas and colorectal cancers. Increased gene copy numbers are detected in 3 of 12 tumor cell lines and 2 of 12 primary pancreatic carcinomas. Overexpresseed in 80% of colorectal cancers. Subunit: Binds DNA. Interacts with SUMO conjugating enzyme UBC9/UBE2I. Interacts with the telomeric protein TERF2IP. Subcellular Location: Nucleus. Tissue Specificity: Liver, skeletal and heart muscle, mammary cells. Very low levels in brain, lung, placenta and kidney. Strongly overexpressed in many pancreas and colorectal cancers. Increased gene copy numbers are detected in 3 of 12 tumor cell lines and 2 of 12 primary pancreatic carcinomas. Overexpressed in 80% of colorectal cancers. Post-translational modifications: Sumoylated. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 10 C2H2-type zinc fingers. SWISS: Q15072 Gene ID: 7705 Database links: Entrez Gene: 7705 Human Entrez Gene: 26465 Mouse Entrez Gene: 677248 Mouse Omim: 601505 Human SwissProt: Q15072 Human SwissProt: Q8BQN6 Mouse Unigene: 643436 Human Unigene: 446516 Mouse Unigene: 456449 Mouse |
