產(chǎn)品編號 | bs-2080R |
英文名稱 | Rabbit Anti-Cecropin-A antibody |
中文名稱 | 抗菌肽/天蠶素抗體 |
別 名 | CECA_HYACE; Cecropin-C; Cecropin; |
產(chǎn)品類型 | 植物抗體 |
研究領(lǐng)域 | 細(xì)菌及病毒 植物 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Hyalophora cecropia) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 4kDa |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide from Hyalophora cecropia Cecropin: 1-37/41 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Cecropins are antimicrobial peptides.They were first isolated from the hemolymph of Hyalophora cecropia, from whence the term cecropin was derived. Cecropins lyse bacterial cell membranes; they also inhibit proline uptake and cause leaky membranes. Cecropins constitute a main part of the cell-free immunity of insects. Cecropins are small proteins of about 31 - 37 amino acid residues active against both Gram-positive and Gram-negative bacteria. Cecropins isolated from insects other than Hyalophora cecropia (Cecropia moth) have been given various names; bactericidin, lepidopteran, sarcotoxin, etc. All of these peptides are structurally related. Cecropin P1, an intestinal antibacterial peptide from Sus scrofa (Pig), also belongs to this family. Cecropin family also consists Cecropin A and Cecropin B. Function: Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria. Subcellular Location: Secreted. Post-translational modifications: A protein with the same sequence as cecropin A, but lacking the carboxyl blocking group, has been isolated and called cecropin C (PubMed:7140755). Similarity: Belongs to the cecropin family. SWISS: P01507 Gene ID: N/A Database links:
Cecropin抗菌肽又稱天蠶素,具有抗菌、抗病毒、抗腫瘤等活性,因其水溶性好,耐高溫,是一種比較理想的抗生素代用品;尤其是其主要抑菌機(jī)制,可破壞細(xì)胞膜的穩(wěn)定性,不易產(chǎn)生耐藥性。 抗菌肽一般是小肽,可以被動物完全消化,不存在殘留性的問題,所以,抗菌肽無論是作為飼料添加劑,獸藥還是人藥,都有理論上的研究價值和生產(chǎn)中的實(shí)際意義。 |