| 產(chǎn)品編號 | bs-0739R |
| 英文名稱 | Rabbit Anti-PAP2c antibody |
| 中文名稱 | 磷脂酸磷酸酶2C抗體 |
| 別 名 | PPAP2C; EC 3.1.3.4; Phosphatidic acid phosphatase 2c; Lipid phosphate phosphohydrolase 2; LPP2; PAP 2c; PAP2 G; PAP2 gamma; Phosphatidic acid phosphatase 2c; Phosphatidic acid phosphatase type 2C; Phosphatidate phosphohydrolase type 2c; Type 2 phosphatidic acid phosphatase gamma; PAP2c; PAP-2c; PAP2G; PAP2-gamma; LPP2_HUMAN; PAP2-G. |
| 研究領(lǐng)域 | 腫瘤 細胞生物 信號轉(zhuǎn)導(dǎo) 激酶和磷酸酶 脂蛋白 新陳代謝 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Cow) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 33kDa |
| 細胞定位 | 細胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PAP2c: 81-276/288 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is similar to phosphatidic acid phosphatase type 2A (PPAP2A) and type 2B (PPAP2B). All three proteins contain 6 transmembrane regions, and a consensus N-glycosylation site. This protein has been shown to possess membrane associated PAP activity. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]. Function: Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). In addition it hydrolyzes lysophosphatidic acid (LPA), ceramide-1-phosphate (C-1-P) and sphingosine-1-phosphate (S-1-P). The relative catalytic efficiency is PA > C-1-P > LPA > S-1-P. Subunit: Homodimer. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Found mainly in brain, pancreas and placenta. Similarity: Belongs to the PA-phosphatase related phosphoesterase family. SWISS: O43688 Gene ID: 8612 Database links: Entrez Gene: 8612 Human Omim: 607126 Human SwissProt: O43688 Human PAP2c-磷脂酸磷酸酶-2C 又稱：PAP2-gamma、PAP2-G主要用于胰島素、糖及脂肪代謝方面的研究。 |
